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Phase I clinical trial of a novel autologous modified-DC vaccine in patients with resected NSCLC
BACKGROUND: The primary aim of this study was to evaluate the safety of a novel dendritic cell (DC) vaccine pulsed with survivin and MUC1, silenced with suppressor of cytokine signaling 1 (SOCS1), and immune stimulated with flagellin for patients with stage I to IIIA non-small cell lung cancer (NSCL...
Autores principales: | Ge, Chunlei, Li, Ruilei, Song, Haifeng, Geng, Tao, Yang, Jinyan, Tan, Qinghua, Song, Linfeng, Wang, Ying, Xue, Yuanbo, Li, Zhen, Dong, Suwei, Zhang, Zhiwei, Zhang, Na, Guo, Jiyin, Hua, Lin, Chen, Siyi, Song, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740508/ https://www.ncbi.nlm.nih.gov/pubmed/29268708 http://dx.doi.org/10.1186/s12885-017-3859-3 |
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