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The Test Your Memory for Mild Cognitive Impairment (TYM-MCI)
BACKGROUND: To validate a short cognitive test: the Test Your Memory for Mild Cognitive Impairment (TYM-MCI) in the diagnosis of patients with amnestic mild cognitive impairment or mild Alzheimer’s disease (aMCI/AD). METHODS: Two hundred and two patients with mild memory problems were recruited. All...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Neurology, Neurosurgery, and Psychiatry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740554/ https://www.ncbi.nlm.nih.gov/pubmed/28912299 http://dx.doi.org/10.1136/jnnp-2016-315327 |
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author | Brown, Jeremy M Lansdall, Claire J Wiggins, Julie Dawson, Kate E Hunter, Kristina Rowe, James B Parker, Richard A |
author_facet | Brown, Jeremy M Lansdall, Claire J Wiggins, Julie Dawson, Kate E Hunter, Kristina Rowe, James B Parker, Richard A |
author_sort | Brown, Jeremy M |
collection | PubMed |
description | BACKGROUND: To validate a short cognitive test: the Test Your Memory for Mild Cognitive Impairment (TYM-MCI) in the diagnosis of patients with amnestic mild cognitive impairment or mild Alzheimer’s disease (aMCI/AD). METHODS: Two hundred and two patients with mild memory problems were recruited. All had ‘passed’ the Mini-Mental State Examination (MMSE). Patients completed the TYM-MCI, the Test Your Memory test (TYM), MMSE and revised Addenbrooke’s Cognitive Examination (ACE-R), had a neurological examination, clinical diagnostics and multidisciplinary team review. RESULTS: As a single test, the TYM-MCI performed as well as the ACE-R in the distinction of patients with aMCI/AD from patients with subjective memory impairment with a sensitivity of 0.79 and specificity of 0.91. Used in combination with the ACE-R, it provided additional value and identified almost all cases of aMCI/AD. The TYM-MCI correctly classified most patients who had equivocal ACE-R scores. Integrated discriminant improvement analysis showed that the TYM-MCI added value to the conventional memory assessment. Patients initially diagnosed as unknown or with subjective memory impairment who were later rediagnosed with aMCI/AD scored poorly on their original TYM-MCI. CONCLUSION: The TYM-MCI is a powerful short cognitive test that examines verbal and visual recall and is a valuable addition to the assessment of patients with aMCI/AD. It is simple and cheap to administer and requires minimal staff time and training. |
format | Online Article Text |
id | pubmed-5740554 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Journal of Neurology, Neurosurgery, and Psychiatry |
record_format | MEDLINE/PubMed |
spelling | pubmed-57405542018-01-03 The Test Your Memory for Mild Cognitive Impairment (TYM-MCI) Brown, Jeremy M Lansdall, Claire J Wiggins, Julie Dawson, Kate E Hunter, Kristina Rowe, James B Parker, Richard A J Neurol Neurosurg Psychiatry Cognitive Neurology BACKGROUND: To validate a short cognitive test: the Test Your Memory for Mild Cognitive Impairment (TYM-MCI) in the diagnosis of patients with amnestic mild cognitive impairment or mild Alzheimer’s disease (aMCI/AD). METHODS: Two hundred and two patients with mild memory problems were recruited. All had ‘passed’ the Mini-Mental State Examination (MMSE). Patients completed the TYM-MCI, the Test Your Memory test (TYM), MMSE and revised Addenbrooke’s Cognitive Examination (ACE-R), had a neurological examination, clinical diagnostics and multidisciplinary team review. RESULTS: As a single test, the TYM-MCI performed as well as the ACE-R in the distinction of patients with aMCI/AD from patients with subjective memory impairment with a sensitivity of 0.79 and specificity of 0.91. Used in combination with the ACE-R, it provided additional value and identified almost all cases of aMCI/AD. The TYM-MCI correctly classified most patients who had equivocal ACE-R scores. Integrated discriminant improvement analysis showed that the TYM-MCI added value to the conventional memory assessment. Patients initially diagnosed as unknown or with subjective memory impairment who were later rediagnosed with aMCI/AD scored poorly on their original TYM-MCI. CONCLUSION: The TYM-MCI is a powerful short cognitive test that examines verbal and visual recall and is a valuable addition to the assessment of patients with aMCI/AD. It is simple and cheap to administer and requires minimal staff time and training. Journal of Neurology, Neurosurgery, and Psychiatry 2017-12 2017-09-14 /pmc/articles/PMC5740554/ /pubmed/28912299 http://dx.doi.org/10.1136/jnnp-2016-315327 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Cognitive Neurology Brown, Jeremy M Lansdall, Claire J Wiggins, Julie Dawson, Kate E Hunter, Kristina Rowe, James B Parker, Richard A The Test Your Memory for Mild Cognitive Impairment (TYM-MCI) |
title | The Test Your Memory for Mild Cognitive Impairment (TYM-MCI) |
title_full | The Test Your Memory for Mild Cognitive Impairment (TYM-MCI) |
title_fullStr | The Test Your Memory for Mild Cognitive Impairment (TYM-MCI) |
title_full_unstemmed | The Test Your Memory for Mild Cognitive Impairment (TYM-MCI) |
title_short | The Test Your Memory for Mild Cognitive Impairment (TYM-MCI) |
title_sort | test your memory for mild cognitive impairment (tym-mci) |
topic | Cognitive Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740554/ https://www.ncbi.nlm.nih.gov/pubmed/28912299 http://dx.doi.org/10.1136/jnnp-2016-315327 |
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