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Rhein lysinate protects renal function in diabetic nephropathy of KK/HlJ mice

The purpose of the present study was to assess the protective effects of rhein lysinate (RHL) in a KK/HlJ mouse model of diabetic nephropathy (DN) and to explore its mechanism of action. A total of 4 groups were established: C57BL/J control, the KK/HlJ model and 25 and 50 mg/kg/day RHL-treated KK/Hl...

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Detalles Bibliográficos
Autores principales: Lin, Ya-Jun, Zhen, Yong-Zhan, Wei, Jing-Bo, Wei, Jie, Dai, Jing, Gao, Jun-Ling, Li, Kai-Ji, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740561/
https://www.ncbi.nlm.nih.gov/pubmed/29285124
http://dx.doi.org/10.3892/etm.2017.5283