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Membrane targeting of inhibitory Smads through palmitoylation controls TGF-β/BMP signaling

TGF-β/BMP (bone morphogenetic protein) signaling pathways play conserved roles in controlling embryonic development, tissue homeostasis, and stem cell regulation. Inhibitory Smads (I-Smads) have been shown to negatively regulate TGF-β/BMP signaling by primarily targeting the type I receptors for ubi...

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Detalles Bibliográficos
Autores principales:	Li, Wenqing, Li, Weini, Zou, Lihui, Ji, Shanming, Li, Chaoyi, Liu, Kehui, Zhang, Guoqiang, Sun, Qinmiao, Xiao, Fei, Chen, Dahua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2017
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740658/ https://www.ncbi.nlm.nih.gov/pubmed/29180412 http://dx.doi.org/10.1073/pnas.1710540114

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