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Upcoming pharmacological developments in chronic hepatitis B: can we glimpse a cure on the horizon?
BACKGROUND: Hepatitis B virus (HBV) chronic infection affects up to 240 million people in the world and it is a common cause of cirrhosis and hepatocellular carcinoma (HCC). HBV covalently closed circular DNA (cccDNA) plays an essential role in HBV persistence and replication. Current pharmacologica...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740721/ https://www.ncbi.nlm.nih.gov/pubmed/29268704 http://dx.doi.org/10.1186/s12876-017-0726-2 |