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Upcoming pharmacological developments in chronic hepatitis B: can we glimpse a cure on the horizon?

BACKGROUND: Hepatitis B virus (HBV) chronic infection affects up to 240 million people in the world and it is a common cause of cirrhosis and hepatocellular carcinoma (HCC). HBV covalently closed circular DNA (cccDNA) plays an essential role in HBV persistence and replication. Current pharmacologica...

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Detalles Bibliográficos
Autores principales: Alonso, Sonia, Guerra, Adriana-René, Carreira, Lourdes, Ferrer, Juan-Ángel, Gutiérrez, María-Luisa, Fernandez-Rodriguez, Conrado M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740721/
https://www.ncbi.nlm.nih.gov/pubmed/29268704
http://dx.doi.org/10.1186/s12876-017-0726-2