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The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer

BACKGROUND: Despite a myriad of attempts in the last three decades to diagnose ovarian cancer (OC) earlier, this clinical aim still remains a significant challenge. Aberrant methylation patterns of linked CpGs analyzed in DNA fragments shed by cancers into the bloodstream (i.e. cell-free DNA) can pr...

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Detalles Bibliográficos
Autores principales:	Widschwendter, Martin, Zikan, Michal, Wahl, Benjamin, Lempiäinen, Harri, Paprotka, Tobias, Evans, Iona, Jones, Allison, Ghazali, Shohreh, Reisel, Daniel, Eichner, Johannes, Rujan, Tamas, Yang, Zhen, Teschendorff, Andrew E., Ryan, Andy, Cibula, David, Menon, Usha, Wittenberger, Timo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740748/ https://www.ncbi.nlm.nih.gov/pubmed/29268796 http://dx.doi.org/10.1186/s13073-017-0500-7

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