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dTCApFs, a derivative of a novel human hormone peptide, induces apoptosis in cancer cells through a mechanism involving loss of Golgi function

dTCApFs (Nerofe™) is a 14-amino acid derivative of a longer hormone peptide, tumor-cells apoptosis factor (TCApF), which enters the cells through the T1/ST2 receptor. In the present study, the mechanism of action (MOA) of dTCApFs as an anticancer agent was investigated. Experiments were performed in...

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Detalles Bibliográficos
Autores principales: Ohana, Joel, Sandler, Uziel, Kass, Gideon, Stemmer, Salomon M., Devary, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740848/
https://www.ncbi.nlm.nih.gov/pubmed/29285362
http://dx.doi.org/10.3892/mco.2017.1453