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Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death
BACKGROUND: Lung ischemia-reperfusion (IR) injury after transplantation as well as acute shortage of suitable donor lungs are two critical issues impacting lung transplant patients. This study investigates the anti-inflammatory and immunomodulatory role of human mesenchymal stromal cells (MSCs) and...
Autores principales: | Stone, Matthew L., Zhao, Yunge, Robert Smith, J., Weiss, Mark L., Kron, Irving L., Laubach, Victor E., Sharma, Ashish K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740880/ https://www.ncbi.nlm.nih.gov/pubmed/29268735 http://dx.doi.org/10.1186/s12931-017-0704-9 |
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Erratum
: Evaluation and reconditioning of donor organs for transplantation through
ex vivo
lung perfusion
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