Cargando…
Selection strategy of phage-displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infection
BACKGROUND: The development of a vaccine for the prevention of visceral leishmaniasis (VL) still represents a significant unmet medical need. A human vaccine can be found if one takes into consideration that many people living in endemic areas of disease are infected but do not develop active VL, in...
Autores principales: | Ramos, Fernanda Fonseca, Costa, Lourena Emanuele, Dias, Daniel Silva, Santos, Thaís Teodoro Oliveira, Rodrigues, Marcella Rezende, Lage, Daniela Pagliara, Salles, Beatriz Cristina Silveira, Martins, Vívian Tamietti, Ribeiro, Patrícia Aparecida Fernandes, Chávez-Fumagalli, Miguel Angel, Dias, Ana Carolina Silva, Alves, Patrícia Terra, Vieira, Érica Leandro Marciano, Roatt, Bruno Mendes, Menezes-Souza, Daniel, Duarte, Mariana Costa, Teixeira, Antonio Lúcio, Goulart, Luiz Ricardo, Coelho, Eduardo Antonio Ferraz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740923/ https://www.ncbi.nlm.nih.gov/pubmed/29268793 http://dx.doi.org/10.1186/s13071-017-2576-8 |
Ejemplares similares
-
Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis
por: Martins, Vivian Tamietti, et al.
Publicado: (2015) -
Correction: Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis
por: Martins, Vivian Tamietti, et al.
Publicado: (2015) -
Mimotope-Based Vaccines of Leishmania infantum Antigens and Their Protective Efficacy against Visceral Leishmaniasis
por: Costa, Lourena Emanuele, et al.
Publicado: (2014) -
A Computational Approach Using Bioinformatics to Screening Drug Targets for Leishmania infantum Species
por: Chávez-Fumagalli, Miguel Angel, et al.
Publicado: (2018) -
Leishmania infantum β-Tubulin Identified by Reverse Engineering Technology through Phage Display Applied as Theranostic Marker for Human Visceral Leishmaniasis
por: Costa, Lourena E., et al.
Publicado: (2019)