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Genetic variation in human drug-related genes

BACKGROUND: Variability in drug efficacy and adverse effects are observed in clinical practice. While the extent of genetic variability in classic pharmacokinetic genes is rather well understood, the role of genetic variation in drug targets is typically less studied. METHODS: Based on 60,706 human...

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Detalles Bibliográficos
Autores principales:	Schärfe, Charlotta Pauline Irmgard, Tremmel, Roman, Schwab, Matthias, Kohlbacher, Oliver, Marks, Debora Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740940/ https://www.ncbi.nlm.nih.gov/pubmed/29273096 http://dx.doi.org/10.1186/s13073-017-0502-5

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