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Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans

Chromatin accessibility, a crucial component of genome regulation, has primarily been studied in homogeneous and simple systems, such as isolated cell populations or early-development models. Whether chromatin accessibility can be assessed in complex, dynamic systems in vivo with high sensitivity re...

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Detalles Bibliográficos
Autores principales: Daugherty, Aaron C., Yeo, Robin W., Buenrostro, Jason D., Greenleaf, William J., Kundaje, Anshul, Brunet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741055/
https://www.ncbi.nlm.nih.gov/pubmed/29141961
http://dx.doi.org/10.1101/gr.226233.117