Genome-wide discovery of active regulatory elements and transcription factor footprints in Caenorhabditis elegans using DNase-seq

Deep sequencing of size-selected DNase I–treated chromatin (DNase-seq) allows high-resolution measurement of chromatin accessibility to DNase I cleavage, permitting identification of de novo active cis-regulatory modules (CRMs) and individual transcription factor (TF) binding sites. We adapted DNase...

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Detalles Bibliográficos
Autores principales: Ho, Margaret C.W., Quintero-Cadena, Porfirio, Sternberg, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741056/
https://www.ncbi.nlm.nih.gov/pubmed/29074739
http://dx.doi.org/10.1101/gr.223735.117

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