Cargando…
Cannabis, cannabinoids, and health
Cannabis (also known as marijuana) is the most frequently used illicit psychoactive substance in the world. Though it was long considered to be a “soft” drug, studies have proven the harmful psychiatric and addictive effects associated with its use. A number of elements are responsible for the incre...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Les Laboratoires Servier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/ https://www.ncbi.nlm.nih.gov/pubmed/29302228 |
_version_ | 1783288144348577792 |
---|---|
author | Lafaye, Genevieve Karila, Laurent Blecha, Lisa Benyamina, Amine |
author_facet | Lafaye, Genevieve Karila, Laurent Blecha, Lisa Benyamina, Amine |
author_sort | Lafaye, Genevieve |
collection | PubMed |
description | Cannabis (also known as marijuana) is the most frequently used illicit psychoactive substance in the world. Though it was long considered to be a “soft” drug, studies have proven the harmful psychiatric and addictive effects associated with its use. A number of elements are responsible for the increased complications of cannabis use, including the increase in the potency of cannabis and an evolution in the ratio between the two primary components, Δ(9)-tetrahydrocannabinol (Δ(9)-THC) and cannabidiol (toward a higher proportion of Δ(9)-THC), Synthetic cannabinoid (SC) use has rapidly progressed over the last few years, primarily among frequent cannabis users, because SCs provide similar psychoactive effects to cannabis. However, their composition and pharmacological properties make them dangerous substances. Cannabis does have therapeutic properties for certain indications. These therapeutic applications pertain only to certain cannabinoids and their synthetic derivatives. The objective of this article is to summarize current developments concerning cannabis and the spread of SCs. Future studies must further explore the benefit-risk profile of medical cannabis use. |
format | Online Article Text |
id | pubmed-5741114 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Les Laboratoires Servier |
record_format | MEDLINE/PubMed |
spelling | pubmed-57411142018-01-04 Cannabis, cannabinoids, and health Lafaye, Genevieve Karila, Laurent Blecha, Lisa Benyamina, Amine Dialogues Clin Neurosci Pharmacological Aspects Cannabis (also known as marijuana) is the most frequently used illicit psychoactive substance in the world. Though it was long considered to be a “soft” drug, studies have proven the harmful psychiatric and addictive effects associated with its use. A number of elements are responsible for the increased complications of cannabis use, including the increase in the potency of cannabis and an evolution in the ratio between the two primary components, Δ(9)-tetrahydrocannabinol (Δ(9)-THC) and cannabidiol (toward a higher proportion of Δ(9)-THC), Synthetic cannabinoid (SC) use has rapidly progressed over the last few years, primarily among frequent cannabis users, because SCs provide similar psychoactive effects to cannabis. However, their composition and pharmacological properties make them dangerous substances. Cannabis does have therapeutic properties for certain indications. These therapeutic applications pertain only to certain cannabinoids and their synthetic derivatives. The objective of this article is to summarize current developments concerning cannabis and the spread of SCs. Future studies must further explore the benefit-risk profile of medical cannabis use. Les Laboratoires Servier 2017-09 /pmc/articles/PMC5741114/ /pubmed/29302228 Text en Copyright: © 2017 AICH - Servier Research Group http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Pharmacological Aspects Lafaye, Genevieve Karila, Laurent Blecha, Lisa Benyamina, Amine Cannabis, cannabinoids, and health |
title | Cannabis, cannabinoids, and health |
title_full | Cannabis, cannabinoids, and health |
title_fullStr | Cannabis, cannabinoids, and health |
title_full_unstemmed | Cannabis, cannabinoids, and health |
title_short | Cannabis, cannabinoids, and health |
title_sort | cannabis, cannabinoids, and health |
topic | Pharmacological Aspects |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741114/ https://www.ncbi.nlm.nih.gov/pubmed/29302228 |
work_keys_str_mv | AT lafayegenevieve cannabiscannabinoidsandhealth AT karilalaurent cannabiscannabinoidsandhealth AT blechalisa cannabiscannabinoidsandhealth AT benyaminaamine cannabiscannabinoidsandhealth |