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A method for the efficient and selective identification of 5-hydroxymethyluracil in genomic DNA

Recently, 5-hydroxymethyluracil (5hmU) was identified in mammalian genomic DNA as an oxidative product of thymine by the ten-eleven translocation (TET) proteins. While the biological role of this modification remains unclear, identifying its genomic location will assist in elucidating function. Here...

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Detalles Bibliográficos
Autores principales:	Bullard, Whitney, Kieft, Rudo, Sabatini, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Methods Manuscript
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741180/ https://www.ncbi.nlm.nih.gov/pubmed/29276783 http://dx.doi.org/10.1093/biomethods/bpw006

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