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Structural constraints and enzymatic promiscuity in the Cas6-dependent generation of crRNAs

A hallmark of defense mechanisms based on clustered regularly interspaced short palindromic repeats (CRISPR) and associated sequences (Cas) are the crRNAs that guide these complexes in the destruction of invading DNA or RNA. Three separate CRISPR-Cas systems exist in the cyanobacterium Synechocystis...

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Detalles Bibliográficos
Autores principales:	Reimann, Viktoria, Alkhnbashi, Omer S., Saunders, Sita J., Scholz, Ingeborg, Hein, Stephanie, Backofen, Rolf, Hess, Wolfgang R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741207/ https://www.ncbi.nlm.nih.gov/pubmed/27599840 http://dx.doi.org/10.1093/nar/gkw786

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