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SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans

Central questions in regenerative biology include how stem cells are maintained and how they transition from self-renewal to differentiation. Germline stem cells (GSCs) in Caeno-rhabditis elegans provide a tractable in vivo model to address these questions. In this system, Notch signaling and PUF RN...

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Detalles Bibliográficos
Autores principales: Shin, Heaji, Haupt, Kimberly A., Kershner, Aaron M., Kroll-Conner, Peggy, Wickens, Marvin, Kimble, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741267/
https://www.ncbi.nlm.nih.gov/pubmed/29232700
http://dx.doi.org/10.1371/journal.pgen.1007121

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