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SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans
Central questions in regenerative biology include how stem cells are maintained and how they transition from self-renewal to differentiation. Germline stem cells (GSCs) in Caeno-rhabditis elegans provide a tractable in vivo model to address these questions. In this system, Notch signaling and PUF RN...
Autores principales: | Shin, Heaji, Haupt, Kimberly A., Kershner, Aaron M., Kroll-Conner, Peggy, Wickens, Marvin, Kimble, Judith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741267/ https://www.ncbi.nlm.nih.gov/pubmed/29232700 http://dx.doi.org/10.1371/journal.pgen.1007121 |
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