Host factors that promote retrotransposon integration are similar in distantly related eukaryotes

Retroviruses and Long Terminal Repeat (LTR)-retrotransposons have distinct patterns of integration sites. The oncogenic potential of retrovirus-based vectors used in gene therapy is dependent on the selection of integration sites associated with promoters. The LTR-retrotransposon Tf1 of Schizosaccha...

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Detalles Bibliográficos
Autores principales: Rai, Sudhir Kumar, Sangesland, Maya, Lee, Michael, Esnault, Caroline, Cui, Yujin, Chatterjee, Atreyi Ghatak, Levin, Henry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741268/
https://www.ncbi.nlm.nih.gov/pubmed/29232693
http://dx.doi.org/10.1371/journal.pgen.1006775

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