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Reduced intraepidermal nerve fiber density after a sustained increase in insular glutamate: a proof-of-concept study examining the pathogenesis of small fiber pathology in fibromyalgia

INTRODUCTION: Neuroimaging reveals increased glutamate within the insula of patients with fibromyalgia (FM), suggesting a link between FM symptoms and increased central excitatory neurotransmission. Many patients with FM also present with decreased intraepidermal nerve fiber density (IENFD), consist...

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Detalles Bibliográficos
Autores principales:	Harte, Steven E., Clauw, Daniel J., Hayes, John M., Feldman, Eva L., St Charles, Irene C., Watson, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2017
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741296/ https://www.ncbi.nlm.nih.gov/pubmed/29392206 http://dx.doi.org/10.1097/PR9.0000000000000590

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