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Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells

Elevated levels of the pro-inflammatory cytokine interleukin-6 (IL-6) have tumor-promoting activity and are associated with poor survival outcomes in many cancers. Additionally, the IL-6/GP130/STAT3 axis has been widely studied due to its pivotal role in tumor development and maintenance in a number...

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Detalles Bibliográficos
Autores principales:	Chen, Xiang, Wei, Jia, Li, Chenglong, Pierson, Christopher R., Finlay, Jonathan L., Lin, Jiayuh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741369/ https://www.ncbi.nlm.nih.gov/pubmed/29207075 http://dx.doi.org/10.3892/ijo.2017.4211

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