NR4A1-induced increase in the sensitivity of a human gastric cancer line to TNFα-mediated apoptosis is associated with the inhibition of JNK/Parkin-dependent mitophagy

Tumor necrosis factor α (TNFα)-based immunotherapy is the vital host defense system against the progression of gastric cancer (GC) as a pro-inflammatory and pro-apoptotic cytokine. However, resistance limits its therapeutic efficiency. Therefore, an increasing number of studies are focusing on the d...

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Detalles Bibliográficos
Autores principales: Yan, Hongzhu, Xiao, Feng, Zou, Jue, Qiu, Chengmin, Sun, Weiwei, Gu, Minmin, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741370/
https://www.ncbi.nlm.nih.gov/pubmed/29207128
http://dx.doi.org/10.3892/ijo.2017.4216

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