Regulation of programmed-death ligand in the human head and neck squamous cell carcinoma microenvironment is mediated through matrix metalloproteinase-mediated proteolytic cleavage

Recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a devastating malignancy with a poor prognosis. According to recent clinical studies, tumour growth can be effectively reduced and survival can be improved by blocking the programmed death receptor-1 (PD-1)/programmed d...

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Detalles Bibliográficos
Autores principales: Hira-Miyazawa, Mayuko, Nakamura, Hiroyuki, Hirai, Mariko, Kobayashi, Yutaka, Kitahara, Hiroko, Bou-Gharios, George, Kawashiri, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741372/
https://www.ncbi.nlm.nih.gov/pubmed/29345283
http://dx.doi.org/10.3892/ijo.2017.4221

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