Fisetin inhibits epidermal growth factor–induced migration of ARPE-19 cells by suppression of AKT activation and Sp1-dependent MMP-9 expression

PURPOSE: Proliferative vitreoretinopathy (PVR) can result in abnormal migration of RPE cells. Fisetin is a naturally occurring compound that has been reported to have antitumor effects, but its effects on epidermal growth factor (EGF)–induced cell migration and the underlying mechanisms remain uncle...

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Detalles Bibliográficos
Autores principales: Lin, Hung-Yu, Chen, Yong-Syuan, Wang, Kai, Chien, Hsiang-Wen, Hsieh, Yi-Hsien, Yang, Shun-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741382/
https://www.ncbi.nlm.nih.gov/pubmed/29296070

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