The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two neurodegenerative diseases in which similar pathogenic mechanisms are involved. Both diseases associate to the high propensity of specific misfolded proteins, like TDP-43 or FUS, to mislocalize and aggregate. This is partl...

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Detalles Bibliográficos
Autores principales: Cristofani, Riccardo, Crippa, Valeria, Vezzoli, Giulia, Rusmini, Paola, Galbiati, Mariarita, Cicardi, Maria Elena, Meroni, Marco, Ferrari, Veronica, Tedesco, Barbara, Piccolella, Margherita, Messi, Elio, Carra, Serena, Poletti, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741577/
https://www.ncbi.nlm.nih.gov/pubmed/28608264
http://dx.doi.org/10.1007/s12192-017-0806-9

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