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Chlamydia abortus Pmp18.1 Induces IL-1β Secretion by TLR4 Activation through the MyD88, NF-κB, and Caspase-1 Signaling Pathways

The polymorphic membrane protein D (Pmp18D) is a 160-kDa outer membrane protein that is conserved and plays an important role in Chlamydia abortus pathogenesis. We have identified an N-terminal fragment of Pmp18D (designated Pmp18.1) as a possible subunit vaccine antigen. In this study, we evaluated...

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Detalles Bibliográficos
Autores principales:	Pan, Qing, Zhang, Qiang, Chu, Jun, Pais, Roshan, Liu, Shanshan, He, Cheng, Eko, Francis O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741698/ https://www.ncbi.nlm.nih.gov/pubmed/29326885 http://dx.doi.org/10.3389/fcimb.2017.00514

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