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Worsened outcome in patients with pancreatic ductal carcinoma on long-term diabetes: association with E-cadherin1 (CDH1) promoter methylation

Prevalence of pancreatic ductal carcinoma (PDC) is nearly twice in patients with diabetes mellitus, but the reason for this close association remains obscure. Recently promoter methylation of E-cadherin1 (CDH1) and CDKN2A genes, encoding E-cadherin and P16 respectively, are invoked in development of...

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Detalles Bibliográficos
Autores principales:	Saito, Takeshi, Mizukami, Hiroki, Umetsu, Satoko, Uchida, Chiaki, Inaba, Wataru, Abe, Makoto, Takahashi, Kazuhisa, Kudo, Kazuhiro, Itabashi, Chieko, Yagihashi, Soroku, Hakamada, Kenichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741711/ https://www.ncbi.nlm.nih.gov/pubmed/29273724 http://dx.doi.org/10.1038/s41598-017-18438-z

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