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Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico
The northern and southern peripheries of ancient Mesoamerica are poorly understood. There has been speculation over whether borderland cultures such as Greater Nicoya and Casas Grandes represent Mesoamerican outposts in the Isthmo-Colombian area and the Greater Southwest, respectively. Poor ancient...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741722/ https://www.ncbi.nlm.nih.gov/pubmed/29273718 http://dx.doi.org/10.1038/s41598-017-18356-0 |
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author | Morales-Arce, Ana Y. Hofman, Courtney A. Duggan, Ana T. Benfer, Adam K. Katzenberg, M. Anne McCafferty, Geoffrey Warinner, Christina |
author_facet | Morales-Arce, Ana Y. Hofman, Courtney A. Duggan, Ana T. Benfer, Adam K. Katzenberg, M. Anne McCafferty, Geoffrey Warinner, Christina |
author_sort | Morales-Arce, Ana Y. |
collection | PubMed |
description | The northern and southern peripheries of ancient Mesoamerica are poorly understood. There has been speculation over whether borderland cultures such as Greater Nicoya and Casas Grandes represent Mesoamerican outposts in the Isthmo-Colombian area and the Greater Southwest, respectively. Poor ancient DNA preservation in these regions challenged previous attempts to resolve these questions using conventional genetic techniques. We apply advanced in-solution mitogenome capture and high-throughput sequencing to fourteen dental samples obtained from the Greater Nicoya sites of Jícaro and La Cascabel in northwest Costa Rica (n = 9; A.D. 800–1250) and the Casas Grandes sites of Paquimé and Convento in northwest Mexico (n = 5; A.D. 1200–1450). Full mitogenome reconstruction was successful for three individuals from Jícaro and five individuals from Paquimé and Convento. The three Jícaro individuals belong to haplogroup B2d, a haplogroup found today only among Central American Chibchan-speakers. The five Paquimé and Convento individuals belong to haplogroups C1c1a, C1c5, B2f and B2a which, are found in contemporary populations in North America and Mesoamerica. We report the first successfully reconstructed ancient mitogenomes from Central America, and the first genetic evidence of ancestry affinity of the ancient inhabitants of Greater Nicoya and Casas Grandes with contemporary Isthmo-Columbian and Greater Southwest populations, respectively. |
format | Online Article Text |
id | pubmed-5741722 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-57417222018-01-03 Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico Morales-Arce, Ana Y. Hofman, Courtney A. Duggan, Ana T. Benfer, Adam K. Katzenberg, M. Anne McCafferty, Geoffrey Warinner, Christina Sci Rep Article The northern and southern peripheries of ancient Mesoamerica are poorly understood. There has been speculation over whether borderland cultures such as Greater Nicoya and Casas Grandes represent Mesoamerican outposts in the Isthmo-Colombian area and the Greater Southwest, respectively. Poor ancient DNA preservation in these regions challenged previous attempts to resolve these questions using conventional genetic techniques. We apply advanced in-solution mitogenome capture and high-throughput sequencing to fourteen dental samples obtained from the Greater Nicoya sites of Jícaro and La Cascabel in northwest Costa Rica (n = 9; A.D. 800–1250) and the Casas Grandes sites of Paquimé and Convento in northwest Mexico (n = 5; A.D. 1200–1450). Full mitogenome reconstruction was successful for three individuals from Jícaro and five individuals from Paquimé and Convento. The three Jícaro individuals belong to haplogroup B2d, a haplogroup found today only among Central American Chibchan-speakers. The five Paquimé and Convento individuals belong to haplogroups C1c1a, C1c5, B2f and B2a which, are found in contemporary populations in North America and Mesoamerica. We report the first successfully reconstructed ancient mitogenomes from Central America, and the first genetic evidence of ancestry affinity of the ancient inhabitants of Greater Nicoya and Casas Grandes with contemporary Isthmo-Columbian and Greater Southwest populations, respectively. Nature Publishing Group UK 2017-12-22 /pmc/articles/PMC5741722/ /pubmed/29273718 http://dx.doi.org/10.1038/s41598-017-18356-0 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Morales-Arce, Ana Y. Hofman, Courtney A. Duggan, Ana T. Benfer, Adam K. Katzenberg, M. Anne McCafferty, Geoffrey Warinner, Christina Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico |
title | Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico |
title_full | Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico |
title_fullStr | Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico |
title_full_unstemmed | Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico |
title_short | Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico |
title_sort | successful reconstruction of whole mitochondrial genomes from ancient central america and mexico |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741722/ https://www.ncbi.nlm.nih.gov/pubmed/29273718 http://dx.doi.org/10.1038/s41598-017-18356-0 |
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