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Diagnosis and treatment of ALT tumors: is Trabectedin a new therapeutic option?
Telomeres are specialized nucleoprotein structures responsible for protecting chromosome ends in order to prevent the loss of genomic information. Telomere maintenance is required for achieving immortality by neoplastic cells. While most cancer cells rely on telomerase re-activation for linear chrom...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741932/ https://www.ncbi.nlm.nih.gov/pubmed/29273061 http://dx.doi.org/10.1186/s13046-017-0657-3 |