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Low frequency of BRAF and KRAS mutations in Chinese patients with low-grade serous carcinoma of the ovary

BACKGROUND: Mounting evidence has shown that KRAS and BRAF are somatic mutations associated with low grade serous carcinoma (LGSC) of the ovary. However, the frequency of KRAS or BRAF mutation was variable in literatures, with a frequency of 16–54% for KRAS mutation and 2–33% for BRAF mutation. Mean...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Bi, Rui, Xiao, Yaoxing, Tu, Xiaoyu, Li, Ming, Li, Anqi, Shan, Ling, Zhou, Shuling, Yang, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741942/
https://www.ncbi.nlm.nih.gov/pubmed/29273082
http://dx.doi.org/10.1186/s13000-017-0679-3