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Nitrous oxide (N(2)O) and subsequent open-label SSRI treatment of adolescents with depression (NOTAD): study protocol for a randomised controlled trial

BACKGROUND: The first line of pharmacological treatment for severe depressive disorders in young people is selective serotonin reuptake inhibitors (SSRIs). However, beneficial clinical effects are rarely observed before several weeks into treatment. Nitrous oxide (N(2)O) has a long-standing safety r...

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Detalles Bibliográficos
Autores principales: Stewart, Richard M., Wong, Janice W. Y., Runions, Kevin C., Rao, Pradeep, Moore, Julia K., Davies, Simon R., von Ungern-Sternberg, Britta S., Sommerfield, David, Zepf, Florian Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741960/
https://www.ncbi.nlm.nih.gov/pubmed/29273063
http://dx.doi.org/10.1186/s13063-017-2342-4