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Nitrous oxide (N(2)O) and subsequent open-label SSRI treatment of adolescents with depression (NOTAD): study protocol for a randomised controlled trial
BACKGROUND: The first line of pharmacological treatment for severe depressive disorders in young people is selective serotonin reuptake inhibitors (SSRIs). However, beneficial clinical effects are rarely observed before several weeks into treatment. Nitrous oxide (N(2)O) has a long-standing safety r...
Autores principales: | Stewart, Richard M., Wong, Janice W. Y., Runions, Kevin C., Rao, Pradeep, Moore, Julia K., Davies, Simon R., von Ungern-Sternberg, Britta S., Sommerfield, David, Zepf, Florian Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741960/ https://www.ncbi.nlm.nih.gov/pubmed/29273063 http://dx.doi.org/10.1186/s13063-017-2342-4 |
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