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Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome

INTRODUCTION: Portal vein thrombosis (PVT) poses an extremely difficult problem in cirrhotic patients who are in need of a liver transplant. The prevalence of PVT in patients with cirrhosis ranges from 0.6% to 26% Nery et al. (2015) [1]. The presence of PVT is associated with more technically diffic...

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Autores principales: Nazzal, Mustafa, Sun, Yifei, Okoye, Obi, Diggs, Laurence, Evans, Neil, Osborn, Tamara, Etesami, Kambiz, Varma, Chintalapati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742012/
https://www.ncbi.nlm.nih.gov/pubmed/29102862
http://dx.doi.org/10.1016/j.ijscr.2017.09.028
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author Nazzal, Mustafa
Sun, Yifei
Okoye, Obi
Diggs, Laurence
Evans, Neil
Osborn, Tamara
Etesami, Kambiz
Varma, Chintalapati
author_facet Nazzal, Mustafa
Sun, Yifei
Okoye, Obi
Diggs, Laurence
Evans, Neil
Osborn, Tamara
Etesami, Kambiz
Varma, Chintalapati
author_sort Nazzal, Mustafa
collection PubMed
description INTRODUCTION: Portal vein thrombosis (PVT) poses an extremely difficult problem in cirrhotic patients who are in need of a liver transplant. The prevalence of PVT in patients with cirrhosis ranges from 0.6% to 26% Nery et al. (2015) [1]. The presence of PVT is associated with more technically difficult liver transplant and in certain cases can be a contraindication to liver transplant. The only option for these patients with extensive PVT would be a multi-visceral transplant, the later unfortunately has a much higher morbidity and mortality compared to liver only transplant Smith et al. (2016) [2]. An alternative approach is needed to provide a safe and reliable outcome. PRESENTATION OF CASE: In this case series, we present our experience with reno-portal shunt as an alternative inflow for the liver allograft. DISCUSSION: This approach appears to be safe with good long-term outcome.Although this technique has been described before, we provide additional considerations that produced good outcomes in our patients. CONCLUSION: We believe that meticulous preoperative planning with high-resolution triple phase CT imaging with a measurement of the diameter of the spleno-renal shunt along with a duplex scan measuring flow through the shunt is key to a successful transplantation. Moreover, appropriate donor liver size is also of extreme importance to avoid portal hypoperfusion.
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spelling pubmed-57420122018-01-02 Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome Nazzal, Mustafa Sun, Yifei Okoye, Obi Diggs, Laurence Evans, Neil Osborn, Tamara Etesami, Kambiz Varma, Chintalapati Int J Surg Case Rep Article INTRODUCTION: Portal vein thrombosis (PVT) poses an extremely difficult problem in cirrhotic patients who are in need of a liver transplant. The prevalence of PVT in patients with cirrhosis ranges from 0.6% to 26% Nery et al. (2015) [1]. The presence of PVT is associated with more technically difficult liver transplant and in certain cases can be a contraindication to liver transplant. The only option for these patients with extensive PVT would be a multi-visceral transplant, the later unfortunately has a much higher morbidity and mortality compared to liver only transplant Smith et al. (2016) [2]. An alternative approach is needed to provide a safe and reliable outcome. PRESENTATION OF CASE: In this case series, we present our experience with reno-portal shunt as an alternative inflow for the liver allograft. DISCUSSION: This approach appears to be safe with good long-term outcome.Although this technique has been described before, we provide additional considerations that produced good outcomes in our patients. CONCLUSION: We believe that meticulous preoperative planning with high-resolution triple phase CT imaging with a measurement of the diameter of the spleno-renal shunt along with a duplex scan measuring flow through the shunt is key to a successful transplantation. Moreover, appropriate donor liver size is also of extreme importance to avoid portal hypoperfusion. Elsevier 2017-10-12 /pmc/articles/PMC5742012/ /pubmed/29102862 http://dx.doi.org/10.1016/j.ijscr.2017.09.028 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Nazzal, Mustafa
Sun, Yifei
Okoye, Obi
Diggs, Laurence
Evans, Neil
Osborn, Tamara
Etesami, Kambiz
Varma, Chintalapati
Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome
title Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome
title_full Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome
title_fullStr Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome
title_full_unstemmed Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome
title_short Reno-portal shunt for liver transplant, an alternative inflow for recipients with grade III–IV portal vein thrombosis: Tips for a better outcome
title_sort reno-portal shunt for liver transplant, an alternative inflow for recipients with grade iii–iv portal vein thrombosis: tips for a better outcome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742012/
https://www.ncbi.nlm.nih.gov/pubmed/29102862
http://dx.doi.org/10.1016/j.ijscr.2017.09.028
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