Co-Stimulation of BCR and Toll-Like Receptor 7 Increases Somatic Hypermutation, Memory B Cell Formation, and Secondary Antibody Response to Protein Antigen

The goal of immunization is to produce both a flood of antibodies to neutralize antigen and memory cells to accelerate the secondary response. To enhance the generation of memory B cells, we examined the effect of co-engaging BCR and toll-like receptor (TLR) 7 receptors by immunizing mice with a hap...

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Detalles Bibliográficos
Autores principales: Castiblanco, Diana P., Maul, Robert W., Russell Knode, Lisa M., Gearhart, Patricia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742111/
https://www.ncbi.nlm.nih.gov/pubmed/29312329
http://dx.doi.org/10.3389/fimmu.2017.01833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742111/
https://www.ncbi.nlm.nih.gov/pubmed/29312329
http://dx.doi.org/10.3389/fimmu.2017.01833

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