Cargando…
The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening
Current applications of human induced pluripotent stem cell (hiPSC) technologies in patient-specific models of neurodegenerative and neuropsychiatric disorders tend to focus on neuronal phenotypes. Here, we review recent efforts toward advancing hiPSCs toward non-neuronal cell types of the central n...
Autores principales: | Gonzalez, David M., Gregory, Jill, Brennand, Kristen J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742170/ https://www.ncbi.nlm.nih.gov/pubmed/29312938 http://dx.doi.org/10.3389/fcell.2017.00117 |
Ejemplares similares
-
Sevoflurane promotes premature differentiation of dopaminergic neurons in hiPSC-derived midbrain organoids
por: Shang, Jia, et al.
Publicado: (2022) -
Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture
por: Gilmozzi, Valentina, et al.
Publicado: (2021) -
Challenges in Physiological Phenotyping of hiPSC-Derived Neurons: From 2D Cultures to 3D Brain Organoids
por: Mateos-Aparicio, Pedro, et al.
Publicado: (2020) -
New considerations for hiPSC-based models of neuropsychiatric disorders
por: Hoffman, Gabriel E., et al.
Publicado: (2018) -
Modeling Human Primary Microcephaly With hiPSC-Derived Brain Organoids Carrying CPAP-E1235V Disease-Associated Mutant Protein
por: An, Hsiao-Lung, et al.
Publicado: (2022)