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De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease

Alterations of lipid metabolism have been frequently associated with Huntington's disease (HD) over the past years. HD is the most common neurodegenerative disorder, with a complex pathogenic profile, typically characterized by progressive striatal and cortical degeneration and associated motor...

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Detalles Bibliográficos
Autores principales: Di Pardo, Alba, Basit, Abdul, Armirotti, Andrea, Amico, Enrico, Castaldo, Salvatore, Pepe, Giuseppe, Marracino, Federico, Buttari, Fabio, Digilio, Anna F., Maglione, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742211/
https://www.ncbi.nlm.nih.gov/pubmed/29311779
http://dx.doi.org/10.3389/fnins.2017.00698