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Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination

Antibody subclasses exhibit extensive polymorphisms (allotypes) that could potentially impact the quality of HIV-vaccine induced B cell responses. Allotypes of immunoglobulin (Ig) G1, the most abundant serum antibody, have been shown to display altered functional properties in regard to serum half-l...

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Detalles Bibliográficos
Autores principales: Kratochvil, Sven, McKay, Paul F., Chung, Amy W., Kent, Stephen J., Gilmour, Jill, Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742328/
https://www.ncbi.nlm.nih.gov/pubmed/29326728
http://dx.doi.org/10.3389/fimmu.2017.01883