Pacific Biosciences Sequencing and IMGT/HighV-QUEST Analysis of Full-Length Single Chain Fragment Variable from an In Vivo Selected Phage-Display Combinatorial Library

Phage-display selection of immunoglobulin (IG) or antibody single chain Fragment variable (scFv) from combinatorial libraries is widely used for identifying new antibodies for novel targets. Next-generation sequencing (NGS) has recently emerged as a new method for the high throughput characterizatio...

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Detalles Bibliográficos
Autores principales: Hemadou, Audrey, Giudicelli, Véronique, Smith, Melissa Laird, Lefranc, Marie-Paule, Duroux, Patrice, Kossida, Sofia, Heiner, Cheryl, Hepler, N. Lance, Kuijpers, John, Groppi, Alexis, Korlach, Jonas, Mondon, Philippe, Ottones, Florence, Jacobin-Valat, Marie-Josée, Laroche-Traineau, Jeanny, Clofent-Sanchez, Gisèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742356/
https://www.ncbi.nlm.nih.gov/pubmed/29326697
http://dx.doi.org/10.3389/fimmu.2017.01796

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