Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections

We report four adult cases of ceftriaxone (CTRX)-induced pseudolithiasis and nephrolithiasis. With the exception of case 1, none of our cases showed abdominal symptoms. Our patients, who had central nervous system (CNS) infections, had been treated with CTRX (4 g/day) for 35-69 days. CTRX-induced ps...

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Autores principales: Tsukagoshi, Setsuki, Ishizawa, Kunihiko, Hirayanagi, Kimitoshi, Nagamine, Shun, Makioka, Kouki, Fujita, Yukio, Ikeda, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742391/
https://www.ncbi.nlm.nih.gov/pubmed/29021458
http://dx.doi.org/10.2169/internalmedicine.8826-17
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author Tsukagoshi, Setsuki
Ishizawa, Kunihiko
Hirayanagi, Kimitoshi
Nagamine, Shun
Makioka, Kouki
Fujita, Yukio
Ikeda, Yoshio
author_facet Tsukagoshi, Setsuki
Ishizawa, Kunihiko
Hirayanagi, Kimitoshi
Nagamine, Shun
Makioka, Kouki
Fujita, Yukio
Ikeda, Yoshio
author_sort Tsukagoshi, Setsuki
collection PubMed
description We report four adult cases of ceftriaxone (CTRX)-induced pseudolithiasis and nephrolithiasis. With the exception of case 1, none of our cases showed abdominal symptoms. Our patients, who had central nervous system (CNS) infections, had been treated with CTRX (4 g/day) for 35-69 days. CTRX-induced pseudolithiasis and nephrolithiasis can appear depending on the total dose of CTRX and the duration for which it is administered. Patients with bacterial CNS infections who are treated with CTRX are typically treated with higher doses for longer periods. It should be recognized that these patients are at higher risk of developing CTRX-induced pseudolithiasis and nephrolithiasis.
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spelling pubmed-57423912017-12-27 Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections Tsukagoshi, Setsuki Ishizawa, Kunihiko Hirayanagi, Kimitoshi Nagamine, Shun Makioka, Kouki Fujita, Yukio Ikeda, Yoshio Intern Med Case Report We report four adult cases of ceftriaxone (CTRX)-induced pseudolithiasis and nephrolithiasis. With the exception of case 1, none of our cases showed abdominal symptoms. Our patients, who had central nervous system (CNS) infections, had been treated with CTRX (4 g/day) for 35-69 days. CTRX-induced pseudolithiasis and nephrolithiasis can appear depending on the total dose of CTRX and the duration for which it is administered. Patients with bacterial CNS infections who are treated with CTRX are typically treated with higher doses for longer periods. It should be recognized that these patients are at higher risk of developing CTRX-induced pseudolithiasis and nephrolithiasis. The Japanese Society of Internal Medicine 2017-10-11 2017-12-01 /pmc/articles/PMC5742391/ /pubmed/29021458 http://dx.doi.org/10.2169/internalmedicine.8826-17 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Tsukagoshi, Setsuki
Ishizawa, Kunihiko
Hirayanagi, Kimitoshi
Nagamine, Shun
Makioka, Kouki
Fujita, Yukio
Ikeda, Yoshio
Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections
title Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections
title_full Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections
title_fullStr Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections
title_full_unstemmed Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections
title_short Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections
title_sort progressive pseudolithiasis associated with the intravenous administration of ceftriaxone in patients with central nervous system infections
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742391/
https://www.ncbi.nlm.nih.gov/pubmed/29021458
http://dx.doi.org/10.2169/internalmedicine.8826-17
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