Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation

Extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is relatively rare. The most commonly reported sites in acute lymphoblastic leukemia (ALL) patients after allo-HSCT are soft tissue and the central nervous system, and the gastrointestinal system is an...

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Detalles Bibliográficos
Autores principales: Ikeuchi, Kazuhiko, Doki, Noriko, Takao, Akinari, Hishima, Tsunekazu, Yamada, Yuta, Konishi, Tatsuya, Nagata, Akihito, Takezaki, Toshiaki, Kaito, Satoshi, Kurosawa, Shuhei, Sakaguchi, Masahiro, Harada, Kaito, Yasuda, Shunichiro, Yoshioka, Kosuke, Watakabe-Inamoto, Kyoko, Igarashi, Aiko, Najima, Yuho, Muto, Hideharu, Kobayashi, Takeshi, Kakihana, Kazuhiko, Sakamaki, Hisashi, Ohashi, Kazuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742396/
https://www.ncbi.nlm.nih.gov/pubmed/28943549
http://dx.doi.org/10.2169/internalmedicine.8646-16
Descripción
Sumario:Extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is relatively rare. The most commonly reported sites in acute lymphoblastic leukemia (ALL) patients after allo-HSCT are soft tissue and the central nervous system, and the gastrointestinal system is an uncommon site. We herein report a unique case with massive hematemesis resulting from gastrointestinal relapse of ALL after allo-HSCT. Upper gastrointestinal endoscopy showed bleeding from a 1.5-cm submucosal tumorous lesion with central ulceration on the anterior wall of the stomach. At the same time, computed tomography revealed extramedullary relapse at the breast and bilateral adrenal glands.

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