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Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation
Extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is relatively rare. The most commonly reported sites in acute lymphoblastic leukemia (ALL) patients after allo-HSCT are soft tissue and the central nervous system, and the gastrointestinal system is an...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japanese Society of Internal Medicine
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742396/ https://www.ncbi.nlm.nih.gov/pubmed/28943549 http://dx.doi.org/10.2169/internalmedicine.8646-16 |
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| author | Ikeuchi, Kazuhiko Doki, Noriko Takao, Akinari Hishima, Tsunekazu Yamada, Yuta Konishi, Tatsuya Nagata, Akihito Takezaki, Toshiaki Kaito, Satoshi Kurosawa, Shuhei Sakaguchi, Masahiro Harada, Kaito Yasuda, Shunichiro Yoshioka, Kosuke Watakabe-Inamoto, Kyoko Igarashi, Aiko Najima, Yuho Muto, Hideharu Kobayashi, Takeshi Kakihana, Kazuhiko Sakamaki, Hisashi Ohashi, Kazuteru |
| author_facet | Ikeuchi, Kazuhiko Doki, Noriko Takao, Akinari Hishima, Tsunekazu Yamada, Yuta Konishi, Tatsuya Nagata, Akihito Takezaki, Toshiaki Kaito, Satoshi Kurosawa, Shuhei Sakaguchi, Masahiro Harada, Kaito Yasuda, Shunichiro Yoshioka, Kosuke Watakabe-Inamoto, Kyoko Igarashi, Aiko Najima, Yuho Muto, Hideharu Kobayashi, Takeshi Kakihana, Kazuhiko Sakamaki, Hisashi Ohashi, Kazuteru |
| author_sort | Ikeuchi, Kazuhiko |
| collection | PubMed |
| description | Extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is relatively rare. The most commonly reported sites in acute lymphoblastic leukemia (ALL) patients after allo-HSCT are soft tissue and the central nervous system, and the gastrointestinal system is an uncommon site. We herein report a unique case with massive hematemesis resulting from gastrointestinal relapse of ALL after allo-HSCT. Upper gastrointestinal endoscopy showed bleeding from a 1.5-cm submucosal tumorous lesion with central ulceration on the anterior wall of the stomach. At the same time, computed tomography revealed extramedullary relapse at the breast and bilateral adrenal glands. |
| format | Online Article Text |
| id | pubmed-5742396 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | The Japanese Society of Internal Medicine |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-57423962017-12-27 Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation Ikeuchi, Kazuhiko Doki, Noriko Takao, Akinari Hishima, Tsunekazu Yamada, Yuta Konishi, Tatsuya Nagata, Akihito Takezaki, Toshiaki Kaito, Satoshi Kurosawa, Shuhei Sakaguchi, Masahiro Harada, Kaito Yasuda, Shunichiro Yoshioka, Kosuke Watakabe-Inamoto, Kyoko Igarashi, Aiko Najima, Yuho Muto, Hideharu Kobayashi, Takeshi Kakihana, Kazuhiko Sakamaki, Hisashi Ohashi, Kazuteru Intern Med Case Report Extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is relatively rare. The most commonly reported sites in acute lymphoblastic leukemia (ALL) patients after allo-HSCT are soft tissue and the central nervous system, and the gastrointestinal system is an uncommon site. We herein report a unique case with massive hematemesis resulting from gastrointestinal relapse of ALL after allo-HSCT. Upper gastrointestinal endoscopy showed bleeding from a 1.5-cm submucosal tumorous lesion with central ulceration on the anterior wall of the stomach. At the same time, computed tomography revealed extramedullary relapse at the breast and bilateral adrenal glands. The Japanese Society of Internal Medicine 2017-09-25 2017-12-01 /pmc/articles/PMC5742396/ /pubmed/28943549 http://dx.doi.org/10.2169/internalmedicine.8646-16 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Case Report Ikeuchi, Kazuhiko Doki, Noriko Takao, Akinari Hishima, Tsunekazu Yamada, Yuta Konishi, Tatsuya Nagata, Akihito Takezaki, Toshiaki Kaito, Satoshi Kurosawa, Shuhei Sakaguchi, Masahiro Harada, Kaito Yasuda, Shunichiro Yoshioka, Kosuke Watakabe-Inamoto, Kyoko Igarashi, Aiko Najima, Yuho Muto, Hideharu Kobayashi, Takeshi Kakihana, Kazuhiko Sakamaki, Hisashi Ohashi, Kazuteru Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation |
| title | Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation |
| title_full | Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation |
| title_fullStr | Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation |
| title_full_unstemmed | Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation |
| title_short | Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation |
| title_sort | extramedullary gastric relapse at the time of bone marrow relapse of acute lymphoblastic leukemia after allogeneic bone marrow transplantation |
| topic | Case Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742396/ https://www.ncbi.nlm.nih.gov/pubmed/28943549 http://dx.doi.org/10.2169/internalmedicine.8646-16 |
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