Cargando…
Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran
BACKGROUND: Studies have shown that Iran has a high rate of opiate abuse and the most prevalently used is opium. This study was aimed to evaluate risk factors in patients with acute opium intoxication who referred to Loghman Hakim Hospital, Tehran, Iran, in 2011. METHODS: A total number of 383 patie...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kerman University of Medical Sciences
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742416/ https://www.ncbi.nlm.nih.gov/pubmed/29299212 |
_version_ | 1783288371165003776 |
---|---|
author | Rismantab-Sani, Sahar Soltani, Babak Soltani, Siamak Memarian, Azadeh |
author_facet | Rismantab-Sani, Sahar Soltani, Babak Soltani, Siamak Memarian, Azadeh |
author_sort | Rismantab-Sani, Sahar |
collection | PubMed |
description | BACKGROUND: Studies have shown that Iran has a high rate of opiate abuse and the most prevalently used is opium. This study was aimed to evaluate risk factors in patients with acute opium intoxication who referred to Loghman Hakim Hospital, Tehran, Iran, in 2011. METHODS: A total number of 383 patients with acute opium overdose, who were referred to the Emergency Department of Loghman Hakim Hospital in Tehran during 2011, were enrolled into this descriptive, cross-sectional study. Clinical data including level of consciousness, vital signs, mode of consumption, medical management, and laboratory results were recorded. Independent t-test was used to analyze the results. FINDINGS: Level of consciousness at admission was lower in patients who expired compared to survivors (P = 0.020). Respiratory depression and tachycardia were both more common among patients who expired compared to survivors (P = 0.001). Increase in urea, creatinine, creatine phosphokinase (CPK), lactate dehydrogenase (LDH), serum glutamic oxaloacetic transaminase (SGOT), and serum glutamic pyruvic transaminase (SGPT) was more common among patients who died compared to survivors and the relationships between death due to opium poisoning and increase in these factors were all statistically significant (P ≤ 0.001). CONCLUSION: The findings of this study clarify the importance of clinical and laboratory findings of patients with opium poisoning in predicting their outcome, although further studies in this context are appreciated. |
format | Online Article Text |
id | pubmed-5742416 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Kerman University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-57424162018-01-03 Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran Rismantab-Sani, Sahar Soltani, Babak Soltani, Siamak Memarian, Azadeh Addict Health Original Article BACKGROUND: Studies have shown that Iran has a high rate of opiate abuse and the most prevalently used is opium. This study was aimed to evaluate risk factors in patients with acute opium intoxication who referred to Loghman Hakim Hospital, Tehran, Iran, in 2011. METHODS: A total number of 383 patients with acute opium overdose, who were referred to the Emergency Department of Loghman Hakim Hospital in Tehran during 2011, were enrolled into this descriptive, cross-sectional study. Clinical data including level of consciousness, vital signs, mode of consumption, medical management, and laboratory results were recorded. Independent t-test was used to analyze the results. FINDINGS: Level of consciousness at admission was lower in patients who expired compared to survivors (P = 0.020). Respiratory depression and tachycardia were both more common among patients who expired compared to survivors (P = 0.001). Increase in urea, creatinine, creatine phosphokinase (CPK), lactate dehydrogenase (LDH), serum glutamic oxaloacetic transaminase (SGOT), and serum glutamic pyruvic transaminase (SGPT) was more common among patients who died compared to survivors and the relationships between death due to opium poisoning and increase in these factors were all statistically significant (P ≤ 0.001). CONCLUSION: The findings of this study clarify the importance of clinical and laboratory findings of patients with opium poisoning in predicting their outcome, although further studies in this context are appreciated. Kerman University of Medical Sciences 2017-04 /pmc/articles/PMC5742416/ /pubmed/29299212 Text en © 2017 Kerman University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Rismantab-Sani, Sahar Soltani, Babak Soltani, Siamak Memarian, Azadeh Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran |
title | Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran |
title_full | Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran |
title_fullStr | Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran |
title_full_unstemmed | Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran |
title_short | Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran |
title_sort | risk factors of mortality due to acute opium poisoning: a report from the largest intoxication referral center in iran |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742416/ https://www.ncbi.nlm.nih.gov/pubmed/29299212 |
work_keys_str_mv | AT rismantabsanisahar riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran AT soltanibabak riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran AT soltanisiamak riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran AT memarianazadeh riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran |