Cargando…

Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran

BACKGROUND: Studies have shown that Iran has a high rate of opiate abuse and the most prevalently used is opium. This study was aimed to evaluate risk factors in patients with acute opium intoxication who referred to Loghman Hakim Hospital, Tehran, Iran, in 2011. METHODS: A total number of 383 patie...

Descripción completa

Detalles Bibliográficos
Autores principales: Rismantab-Sani, Sahar, Soltani, Babak, Soltani, Siamak, Memarian, Azadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kerman University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742416/
https://www.ncbi.nlm.nih.gov/pubmed/29299212
_version_ 1783288371165003776
author Rismantab-Sani, Sahar
Soltani, Babak
Soltani, Siamak
Memarian, Azadeh
author_facet Rismantab-Sani, Sahar
Soltani, Babak
Soltani, Siamak
Memarian, Azadeh
author_sort Rismantab-Sani, Sahar
collection PubMed
description BACKGROUND: Studies have shown that Iran has a high rate of opiate abuse and the most prevalently used is opium. This study was aimed to evaluate risk factors in patients with acute opium intoxication who referred to Loghman Hakim Hospital, Tehran, Iran, in 2011. METHODS: A total number of 383 patients with acute opium overdose, who were referred to the Emergency Department of Loghman Hakim Hospital in Tehran during 2011, were enrolled into this descriptive, cross-sectional study. Clinical data including level of consciousness, vital signs, mode of consumption, medical management, and laboratory results were recorded. Independent t-test was used to analyze the results. FINDINGS: Level of consciousness at admission was lower in patients who expired compared to survivors (P = 0.020). Respiratory depression and tachycardia were both more common among patients who expired compared to survivors (P = 0.001). Increase in urea, creatinine, creatine phosphokinase (CPK), lactate dehydrogenase (LDH), serum glutamic oxaloacetic transaminase (SGOT), and serum glutamic pyruvic transaminase (SGPT) was more common among patients who died compared to survivors and the relationships between death due to opium poisoning and increase in these factors were all statistically significant (P ≤ 0.001). CONCLUSION: The findings of this study clarify the importance of clinical and laboratory findings of patients with opium poisoning in predicting their outcome, although further studies in this context are appreciated.
format Online
Article
Text
id pubmed-5742416
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Kerman University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-57424162018-01-03 Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran Rismantab-Sani, Sahar Soltani, Babak Soltani, Siamak Memarian, Azadeh Addict Health Original Article BACKGROUND: Studies have shown that Iran has a high rate of opiate abuse and the most prevalently used is opium. This study was aimed to evaluate risk factors in patients with acute opium intoxication who referred to Loghman Hakim Hospital, Tehran, Iran, in 2011. METHODS: A total number of 383 patients with acute opium overdose, who were referred to the Emergency Department of Loghman Hakim Hospital in Tehran during 2011, were enrolled into this descriptive, cross-sectional study. Clinical data including level of consciousness, vital signs, mode of consumption, medical management, and laboratory results were recorded. Independent t-test was used to analyze the results. FINDINGS: Level of consciousness at admission was lower in patients who expired compared to survivors (P = 0.020). Respiratory depression and tachycardia were both more common among patients who expired compared to survivors (P = 0.001). Increase in urea, creatinine, creatine phosphokinase (CPK), lactate dehydrogenase (LDH), serum glutamic oxaloacetic transaminase (SGOT), and serum glutamic pyruvic transaminase (SGPT) was more common among patients who died compared to survivors and the relationships between death due to opium poisoning and increase in these factors were all statistically significant (P ≤ 0.001). CONCLUSION: The findings of this study clarify the importance of clinical and laboratory findings of patients with opium poisoning in predicting their outcome, although further studies in this context are appreciated. Kerman University of Medical Sciences 2017-04 /pmc/articles/PMC5742416/ /pubmed/29299212 Text en © 2017 Kerman University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Rismantab-Sani, Sahar
Soltani, Babak
Soltani, Siamak
Memarian, Azadeh
Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran
title Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran
title_full Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran
title_fullStr Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran
title_full_unstemmed Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran
title_short Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran
title_sort risk factors of mortality due to acute opium poisoning: a report from the largest intoxication referral center in iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742416/
https://www.ncbi.nlm.nih.gov/pubmed/29299212
work_keys_str_mv AT rismantabsanisahar riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran
AT soltanibabak riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran
AT soltanisiamak riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran
AT memarianazadeh riskfactorsofmortalityduetoacuteopiumpoisoningareportfromthelargestintoxicationreferralcenteriniran