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Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model

Mycobacterium tuberculosis is the pathogenic bacterium that causes tuberculosis (TB), one of the most lethal infectious diseases in the world. The only vaccine against TB is minimally protective, and multi-drug resistant TB necessitates new therapeutics to treat infection. Developing new therapies r...

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Detalles Bibliográficos
Autores principales:	Warsinske, Hayley C., Pienaar, Elsje, Linderman, Jennifer J., Mattila, Joshua T., Kirschner, Denise E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742530/ https://www.ncbi.nlm.nih.gov/pubmed/29326718 http://dx.doi.org/10.3389/fimmu.2017.01843

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