Higher O-GlcNAc Levels Are Associated with Defects in Progenitor Proliferation and Premature Neuronal Differentiation during in-Vitro Human Embryonic Cortical Neurogenesis

The nutrient responsive O-GlcNAcylation is a dynamic post-translational protein modification found on several nucleocytoplasmic proteins. Previous studies have suggested that hyperglycemia induces the levels of total O-GlcNAcylation inside the cells. Hyperglycemia mediated increase in protein O-GlcN...

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Detalles Bibliográficos
Autores principales: Parween, Shama, Varghese, Divya S., Ardah, Mustafa T., Prabakaran, Ashok D., Mensah-Brown, Eric, Emerald, Bright Starling, Ansari, Suraiya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742625/
https://www.ncbi.nlm.nih.gov/pubmed/29311838
http://dx.doi.org/10.3389/fncel.2017.00415

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