Metformin protects against intestinal barrier dysfunction via AMPKα1‐dependent inhibition of JNK signalling activation

Disruption of the intestinal epithelial barrier, that involves the activation of C‐Jun N‐terminal kinase (JNK), contributes to initiate and accelerate inflammation in inflammatory bowel disease. Metformin has unexpected beneficial effects other than glucose‐lowering effects. Here, we provided eviden...

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Detalles Bibliográficos
Autores principales: Deng, Jun, Zeng, Lishan, Lai, Xueying, Li, Jing, Liu, Le, Lin, Qianyun, Chen, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742676/
https://www.ncbi.nlm.nih.gov/pubmed/29148173
http://dx.doi.org/10.1111/jcmm.13342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742676/
https://www.ncbi.nlm.nih.gov/pubmed/29148173
http://dx.doi.org/10.1111/jcmm.13342

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