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Impaired erythropoietin synthesis in chronic kidney disease is caused by alterations in extracellular matrix composition
Renal fibrosis and anaemia are two of the most relevant events in chronic kidney disease. Fibrosis is characterized by the accumulation of extracellular matrix proteins in the glomeruli and tubular interstitium. Anaemia is the consequence of a decrease in erythropoietin production in fibrotic kidney...
Autores principales: | Olmos, Gemma, Muñoz‐Félix, José M., Mora, Inés, Müller, Anton Gerhard, Ruiz‐Torres, Maria Piedad, López‐Novoa, José M., Rodríguez‐Puyol, Diego |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742742/ https://www.ncbi.nlm.nih.gov/pubmed/28857467 http://dx.doi.org/10.1111/jcmm.13319 |
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