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Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions

Since Huggins defined the androgen-sensitive nature of prostate cancer (PCa), suppression of systemic testosterone (T) has remained the most effective initial therapy for advanced disease although progression inevitably occurs. From the inception of clinical efforts to suppress androgen receptor (AR...

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Detalles Bibliográficos
Autores principales:	Mohammad, Osama S., Nyquist, Michael D., Schweizer, Michael T., Balk, Stephen P., Corey, Eva, Plymate, Stephen, Nelson, Peter S., Mostaghel, Elahe A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742814/ https://www.ncbi.nlm.nih.gov/pubmed/29210989 http://dx.doi.org/10.3390/cancers9120166

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