New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides

A novel cytotoxic diterpenoid, chabrolin A (1) (possessing an unprecedented terpenoid skeleton), as well as three new cytotoxic sesquiterpenoids, parathyrsoidins E–G (2–4), were isolated by cytotoxicity-guided fractionation from soft corals Nephthea chabroli and Paralemnalia thyrsoides. The structur...

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Detalles Bibliográficos
Autores principales: Lee, Yu-Sheng, Duh, Tsai-Hui, Siao, Shu-Sheng, Chang, Rey-Chang, Wang, Shang-Kwei, Duh, Chang-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742852/
https://www.ncbi.nlm.nih.gov/pubmed/29257046
http://dx.doi.org/10.3390/md15120392
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author Lee, Yu-Sheng
Duh, Tsai-Hui
Siao, Shu-Sheng
Chang, Rey-Chang
Wang, Shang-Kwei
Duh, Chang-Yih
author_facet Lee, Yu-Sheng
Duh, Tsai-Hui
Siao, Shu-Sheng
Chang, Rey-Chang
Wang, Shang-Kwei
Duh, Chang-Yih
author_sort Lee, Yu-Sheng
collection PubMed
description A novel cytotoxic diterpenoid, chabrolin A (1) (possessing an unprecedented terpenoid skeleton), as well as three new cytotoxic sesquiterpenoids, parathyrsoidins E–G (2–4), were isolated by cytotoxicity-guided fractionation from soft corals Nephthea chabroli and Paralemnalia thyrsoides. The structures of the new compounds were determined by extensive analysis of spectroscopic data.
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spelling pubmed-57428522017-12-29 New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides Lee, Yu-Sheng Duh, Tsai-Hui Siao, Shu-Sheng Chang, Rey-Chang Wang, Shang-Kwei Duh, Chang-Yih Mar Drugs Article A novel cytotoxic diterpenoid, chabrolin A (1) (possessing an unprecedented terpenoid skeleton), as well as three new cytotoxic sesquiterpenoids, parathyrsoidins E–G (2–4), were isolated by cytotoxicity-guided fractionation from soft corals Nephthea chabroli and Paralemnalia thyrsoides. The structures of the new compounds were determined by extensive analysis of spectroscopic data. MDPI 2017-12-19 /pmc/articles/PMC5742852/ /pubmed/29257046 http://dx.doi.org/10.3390/md15120392 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Yu-Sheng
Duh, Tsai-Hui
Siao, Shu-Sheng
Chang, Rey-Chang
Wang, Shang-Kwei
Duh, Chang-Yih
New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides
title New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides
title_full New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides
title_fullStr New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides
title_full_unstemmed New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides
title_short New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides
title_sort new cytotoxic terpenoids from soft corals nephthea chabroli and paralemnalia thyrsoides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742852/
https://www.ncbi.nlm.nih.gov/pubmed/29257046
http://dx.doi.org/10.3390/md15120392
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