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Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases
GSK-3 is a ubiquitously expressed serine/threonine kinase existing as GSK-3α and GSK-3β isoforms, both active under basal conditions and inactivated upon phosphorylation by different upstream kinases. Initially discovered as a regulator of glycogen synthesis, GSK-3 is also involved in several signal...
Autores principales: | Mancinelli, Romina, Carpino, Guido, Petrungaro, Simonetta, Mammola, Caterina Loredana, Tomaipitinca, Luana, Filippini, Antonio, Facchiano, Antonio, Ziparo, Elio, Giampietri, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742885/ https://www.ncbi.nlm.nih.gov/pubmed/29379583 http://dx.doi.org/10.1155/2017/4629495 |
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