Diabetes Mellitus and Risk of Hepatocellular Carcinoma

The occurrence of hepatocellular carcinoma (HCC) is two to three times higher in patients with diabetes mellitus (DM), the prevalence of which is increasing sharply worldwide. The purpose of this review was to describe clinical links between DM and HCC and potential biological mechanisms that may ac...

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Detalles Bibliográficos
Autores principales: Li, Xu, Wang, Xiaocong, Gao, Pujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742888/
https://www.ncbi.nlm.nih.gov/pubmed/29379799
http://dx.doi.org/10.1155/2017/5202684
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author Li, Xu
Wang, Xiaocong
Gao, Pujun
author_facet Li, Xu
Wang, Xiaocong
Gao, Pujun
author_sort Li, Xu
collection PubMed
description The occurrence of hepatocellular carcinoma (HCC) is two to three times higher in patients with diabetes mellitus (DM), the prevalence of which is increasing sharply worldwide. The purpose of this review was to describe clinical links between DM and HCC and potential biological mechanisms that may account for this association. We evaluated the role of potential pathways that could account for the development of HCC with different etiologies in the presence of DM. In addition, we also briefly discuss the potential effect of other factors such as type and dosage of antidiabetic medicines and duration of DM on HCC risk.
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spelling pubmed-57428882018-01-29 Diabetes Mellitus and Risk of Hepatocellular Carcinoma Li, Xu Wang, Xiaocong Gao, Pujun Biomed Res Int Review Article The occurrence of hepatocellular carcinoma (HCC) is two to three times higher in patients with diabetes mellitus (DM), the prevalence of which is increasing sharply worldwide. The purpose of this review was to describe clinical links between DM and HCC and potential biological mechanisms that may account for this association. We evaluated the role of potential pathways that could account for the development of HCC with different etiologies in the presence of DM. In addition, we also briefly discuss the potential effect of other factors such as type and dosage of antidiabetic medicines and duration of DM on HCC risk. Hindawi 2017 2017-12-12 /pmc/articles/PMC5742888/ /pubmed/29379799 http://dx.doi.org/10.1155/2017/5202684 Text en Copyright © 2017 Xu Li et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Li, Xu
Wang, Xiaocong
Gao, Pujun
Diabetes Mellitus and Risk of Hepatocellular Carcinoma
title Diabetes Mellitus and Risk of Hepatocellular Carcinoma
title_full Diabetes Mellitus and Risk of Hepatocellular Carcinoma
title_fullStr Diabetes Mellitus and Risk of Hepatocellular Carcinoma
title_full_unstemmed Diabetes Mellitus and Risk of Hepatocellular Carcinoma
title_short Diabetes Mellitus and Risk of Hepatocellular Carcinoma
title_sort diabetes mellitus and risk of hepatocellular carcinoma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742888/
https://www.ncbi.nlm.nih.gov/pubmed/29379799
http://dx.doi.org/10.1155/2017/5202684
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AT wangxiaocong diabetesmellitusandriskofhepatocellularcarcinoma
AT gaopujun diabetesmellitusandriskofhepatocellularcarcinoma

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