CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter

The innate immune system protects against infections by initiating an inducible inflammatory response. NF-κB is one of the critical transcription factors controlling this complex response, but some aspects of its regulation remain unclear. For example, although long non-coding RNAs (lncRNAs) have be...

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Detalles Bibliográficos
Autores principales: Covarrubias, Sergio, Robinson, Elektra K., Shapleigh, Barbara, Vollmers, Apple, Katzman, Sol, Hanley, Nicole, Fong, Nicholas, McManus, Michael T., Carpenter, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743067/
https://www.ncbi.nlm.nih.gov/pubmed/29051223
http://dx.doi.org/10.1074/jbc.M117.799155

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