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Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland

OBJECTIVES: The aim of the study was to evaluate the oncologic and functional long‐term outcome after surgical therapy of pleomorphic adenomas of the submandibular gland. METHODS: The medical charts of all patients treated for pleomorphic adenomas of the submandibular gland by means of submandibulec...

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Autores principales: Mantsopoulos, Konstantinos, Goncalves, Miguel, Schapher, Mirco, Iro, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743162/
https://www.ncbi.nlm.nih.gov/pubmed/29299510
http://dx.doi.org/10.1002/lio2.113
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author Mantsopoulos, Konstantinos
Goncalves, Miguel
Schapher, Mirco
Iro, Heinrich
author_facet Mantsopoulos, Konstantinos
Goncalves, Miguel
Schapher, Mirco
Iro, Heinrich
author_sort Mantsopoulos, Konstantinos
collection PubMed
description OBJECTIVES: The aim of the study was to evaluate the oncologic and functional long‐term outcome after surgical therapy of pleomorphic adenomas of the submandibular gland. METHODS: The medical charts of all patients treated for pleomorphic adenomas of the submandibular gland by means of submandibulectomy between 2000 and 2016 were studied retrospectively. Patients who had had revision after external primary surgery, as well as patients with insufficient data were excluded from our study sample. RESULTS: A total of 75 patients formed our study sample (28 men, 47 women, male:female ratio 0.59:1). Their mean age was 48 years (14–78 years). Mean follow‐up was 82 months (12–170 months). No recurrences of a pleomorphic adenoma could be detected in our study cases. Normal facial nerve function (House‐Brackmann grade I) in the direct postoperative phase was shown in 54/75 cases (72%). In the remaining 21/75 cases (28%), mild paresis of the marginal mandibular branch of the facial nerve (House‐Brackmann II) could be detected in the direct postoperative phase. All cases with facial palsy had recovered with normal facial nerve function (House‐Brackmann I) in 3–6 months. CONCLUSION: Our study was able to show oncologic and consistently acceptable oncologic and functional outcomes after submandibulectomy for pleomorphic adenomas of the submandibular gland. LEVEL OF EVIDENCE: 4.
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spelling pubmed-57431622018-01-03 Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland Mantsopoulos, Konstantinos Goncalves, Miguel Schapher, Mirco Iro, Heinrich Laryngoscope Investig Otolaryngol Head and Neck, and Tumor Biology OBJECTIVES: The aim of the study was to evaluate the oncologic and functional long‐term outcome after surgical therapy of pleomorphic adenomas of the submandibular gland. METHODS: The medical charts of all patients treated for pleomorphic adenomas of the submandibular gland by means of submandibulectomy between 2000 and 2016 were studied retrospectively. Patients who had had revision after external primary surgery, as well as patients with insufficient data were excluded from our study sample. RESULTS: A total of 75 patients formed our study sample (28 men, 47 women, male:female ratio 0.59:1). Their mean age was 48 years (14–78 years). Mean follow‐up was 82 months (12–170 months). No recurrences of a pleomorphic adenoma could be detected in our study cases. Normal facial nerve function (House‐Brackmann grade I) in the direct postoperative phase was shown in 54/75 cases (72%). In the remaining 21/75 cases (28%), mild paresis of the marginal mandibular branch of the facial nerve (House‐Brackmann II) could be detected in the direct postoperative phase. All cases with facial palsy had recovered with normal facial nerve function (House‐Brackmann I) in 3–6 months. CONCLUSION: Our study was able to show oncologic and consistently acceptable oncologic and functional outcomes after submandibulectomy for pleomorphic adenomas of the submandibular gland. LEVEL OF EVIDENCE: 4. John Wiley and Sons Inc. 2017-10-16 /pmc/articles/PMC5743162/ /pubmed/29299510 http://dx.doi.org/10.1002/lio2.113 Text en © 2017 The Authors Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Head and Neck, and Tumor Biology
Mantsopoulos, Konstantinos
Goncalves, Miguel
Schapher, Mirco
Iro, Heinrich
Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
title Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
title_full Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
title_fullStr Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
title_full_unstemmed Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
title_short Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
title_sort long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
topic Head and Neck, and Tumor Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743162/
https://www.ncbi.nlm.nih.gov/pubmed/29299510
http://dx.doi.org/10.1002/lio2.113
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