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Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland
OBJECTIVES: The aim of the study was to evaluate the oncologic and functional long‐term outcome after surgical therapy of pleomorphic adenomas of the submandibular gland. METHODS: The medical charts of all patients treated for pleomorphic adenomas of the submandibular gland by means of submandibulec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743162/ https://www.ncbi.nlm.nih.gov/pubmed/29299510 http://dx.doi.org/10.1002/lio2.113 |
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author | Mantsopoulos, Konstantinos Goncalves, Miguel Schapher, Mirco Iro, Heinrich |
author_facet | Mantsopoulos, Konstantinos Goncalves, Miguel Schapher, Mirco Iro, Heinrich |
author_sort | Mantsopoulos, Konstantinos |
collection | PubMed |
description | OBJECTIVES: The aim of the study was to evaluate the oncologic and functional long‐term outcome after surgical therapy of pleomorphic adenomas of the submandibular gland. METHODS: The medical charts of all patients treated for pleomorphic adenomas of the submandibular gland by means of submandibulectomy between 2000 and 2016 were studied retrospectively. Patients who had had revision after external primary surgery, as well as patients with insufficient data were excluded from our study sample. RESULTS: A total of 75 patients formed our study sample (28 men, 47 women, male:female ratio 0.59:1). Their mean age was 48 years (14–78 years). Mean follow‐up was 82 months (12–170 months). No recurrences of a pleomorphic adenoma could be detected in our study cases. Normal facial nerve function (House‐Brackmann grade I) in the direct postoperative phase was shown in 54/75 cases (72%). In the remaining 21/75 cases (28%), mild paresis of the marginal mandibular branch of the facial nerve (House‐Brackmann II) could be detected in the direct postoperative phase. All cases with facial palsy had recovered with normal facial nerve function (House‐Brackmann I) in 3–6 months. CONCLUSION: Our study was able to show oncologic and consistently acceptable oncologic and functional outcomes after submandibulectomy for pleomorphic adenomas of the submandibular gland. LEVEL OF EVIDENCE: 4. |
format | Online Article Text |
id | pubmed-5743162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57431622018-01-03 Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland Mantsopoulos, Konstantinos Goncalves, Miguel Schapher, Mirco Iro, Heinrich Laryngoscope Investig Otolaryngol Head and Neck, and Tumor Biology OBJECTIVES: The aim of the study was to evaluate the oncologic and functional long‐term outcome after surgical therapy of pleomorphic adenomas of the submandibular gland. METHODS: The medical charts of all patients treated for pleomorphic adenomas of the submandibular gland by means of submandibulectomy between 2000 and 2016 were studied retrospectively. Patients who had had revision after external primary surgery, as well as patients with insufficient data were excluded from our study sample. RESULTS: A total of 75 patients formed our study sample (28 men, 47 women, male:female ratio 0.59:1). Their mean age was 48 years (14–78 years). Mean follow‐up was 82 months (12–170 months). No recurrences of a pleomorphic adenoma could be detected in our study cases. Normal facial nerve function (House‐Brackmann grade I) in the direct postoperative phase was shown in 54/75 cases (72%). In the remaining 21/75 cases (28%), mild paresis of the marginal mandibular branch of the facial nerve (House‐Brackmann II) could be detected in the direct postoperative phase. All cases with facial palsy had recovered with normal facial nerve function (House‐Brackmann I) in 3–6 months. CONCLUSION: Our study was able to show oncologic and consistently acceptable oncologic and functional outcomes after submandibulectomy for pleomorphic adenomas of the submandibular gland. LEVEL OF EVIDENCE: 4. John Wiley and Sons Inc. 2017-10-16 /pmc/articles/PMC5743162/ /pubmed/29299510 http://dx.doi.org/10.1002/lio2.113 Text en © 2017 The Authors Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Head and Neck, and Tumor Biology Mantsopoulos, Konstantinos Goncalves, Miguel Schapher, Mirco Iro, Heinrich Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland |
title | Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland |
title_full | Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland |
title_fullStr | Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland |
title_full_unstemmed | Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland |
title_short | Long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland |
title_sort | long‐term oncologic and functional outcome in pleomorphic adenomas of the submandibular gland |
topic | Head and Neck, and Tumor Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743162/ https://www.ncbi.nlm.nih.gov/pubmed/29299510 http://dx.doi.org/10.1002/lio2.113 |
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